Challenging Conventional Thinking on Weight/Reps

From Sweat Science

They found that the first (high weight, low reps) and third routines (low weight, high reps) were the same on most measures of protein synthesis, and the third routine was even better on some measures. Those new proteins being synthesized are what accumulate, over time, to produce bigger muscles. So as long as you’re lifting until can’t lift anymore, you’ll do as well or better with light weights as you would with heavy weights....This is some serious heresy being proposed, and it’s important to note that they didn’t actually observe bigger muscles, just cellular markers. The researchers themselves note that “a training study in which these distinctly different exercise loads are utilized is clearly warranted to confirm our speculation.”